NHTSA lists 1 safety recall and 99 owner complaints for the 2006 Lexus RX330. Most complaints involve structure (18) and engine (13). The EPA rates it 18–20 mpg combined.
TOYOTA IS RECALLING CERTAIN MODEL YEAR 2004-2006 HIGHLANDER, HIGHLANDER HYBRID, AND MODEL YEAR 2004-2007 LEXUS RX330, RX350, AND RX400H VEHICLES. IF THE FORWARD RETENTION CLIP USED TO SECURE THE FLOOR CARPET COVER, WHICH IS LOCATED IN FRONT OF THE CENTER CONSOLE, IS NOT INSTALLED PROPERLY THE COVER MAY LEAN TOWARD THE ACCELERATOR PEDAL AND INTERFERE WITH THE ACCELERATOR PEDAL ARM.
Complaints are unverified owner reports to NHTSA and are not normalized for sales volume. One complaint can cite several components.
“My car exploded- huge fire. I was not driving- it had been parked. The fire marshal indicated that it was an electrical problem located near the battery. There we no indicators of any issues. I only had liability on the car- so i am out of luck. but the NYFD inspected. It happened on Wednesday 9/29/21. Was inspected on 9/30.”
“My vehicle runs hot after just five minutes and steam or smoke starts emitting from engine with a strange smell. It left me stranded on a narrow and busy highway where I felt unsafe”
“2006 Lexus RX 400h didn't stop even after breaks were applied, it did continue to move forward and slowly push another car for about 15 feet until another car hit a pile of dirt.”
Towing, payload and dimensions aren’t in the EPA or NHTSA data, so we don’t list them.
| Version | City | Hwy | Comb. | Fuel / yr | CO₂ g/mi |
|---|---|---|---|---|---|
| RX 330 2WD Auto 5-spd, 6 cyl, 3.3 L · Front-Wheel Drive | 17 | 23 | 20 | $4,000 | 444 |
| RX 330 2WD Auto (S5), 6 cyl, 3.3 L · Front-Wheel Drive | 17 | 23 | 19 | $4,200 | 468 |
| RX 330 4WD Auto 5-spd, 6 cyl, 3.3 L · 4-Wheel or All-Wheel Drive | 16 | 22 | 19 | $4,200 | 468 |
| RX 330 4WD Auto (S5), 6 cyl, 3.3 L · 4-Wheel or All-Wheel Drive | 16 | 22 | 18 | $4,400 | 494 |
| Item | Miles | Time | Note |
|---|---|---|---|
| Engine oil & filter | 5,000–10,000 mi | 6–12 months | Follow the oil-life monitor if fitted |
| Tire rotation | 5,000–7,500 mi | Every oil change | Check pressure monthly |
| Engine air filter | 15,000–30,000 mi | 1–2 years | Sooner in dusty areas |
| Cabin air filter | 15,000–25,000 mi | 1–2 years | |
| Brake fluid | — | 2–3 years | Absorbs moisture over time |
| Coolant | 60,000–100,000 mi | 5–10 years | Long-life coolants last longer |
| Spark plugs | 60,000–100,000 mi | — | Iridium/platinum plugs at the long end |
| 12V battery | — | 3–5 years | Heat shortens battery life |
1 safety recall as of Oct 28, 2026, according to NHTSA. Recall repairs are free at a dealer. Check your VIN to see whether your car is included and whether the repair was done.
Owners filed 99 complaints with NHTSA. The most-cited components are structure (18), engine (13), vehicle speed control (13). Complaints are unverified owner reports and aren't adjusted for how many cars were sold.
The EPA rates the 2006 Lexus RX330 at 18–20 mpg combined, depending on engine and drivetrain (4 versions rated).