2021 Lexus RX 350Recalls, problems, MPG & safety
NHTSA lists 0 safety recalls and 71 owner complaints for the 2021 Lexus RX 350. Most complaints involve air bags (47) and structure (5). The EPA rates it 22–23 mpg combined, and NHTSA gives it 4–5 stars overall.
Safety recalls
Owner complaints by component
- Air bags47
- Structure5
- Electrical system4
- Service brakes4
- Forward collision avoidance4
- Seat belts4
- Tires2
- Engine2
- Visibility/wiper1
Complaints are unverified owner reports to NHTSA and are not normalized for sales volume. One complaint can cite several components.
What owners report most
Air bags
“The contact owns a 2021 Lexus RX 350. The contact received notification of NHTSA Campaign Number: 23V865000 (Air Bags); however, the part to do the recall repair was not yet available. The local dealer was contacted. The contact stated that the manufacturer had exceeded a reasonable amount of time for the recall repair. The manufacturer was not made aware of the issue. The contact had not experienced a failure.”
Structure
“I was at the gas station, in line waiting for one of the three gas pumps to be available. I put my car in reverse to back up and pull around another car in order to go to the open pump in front. When my car was in reverse motion, I stepped on the brake pedal, but the car did not stop. I stepped on the brake pedal numerous times, but the brake did not function. My car backed into the front of the car in line behind me damaging both vehicles. The automatic emergency braking system did not activate, and there was no rear collision warning sound or message. I switched my car from Reverse into Park to stop its movement, but it was too late to avoid the collision. I had a passenger in my car who corroborates this description. Fortunately there were no pedestrians behind my car, so the only damage was to the vehicles. My vehicle has not been inspected by anyone since the accident, but will be soon. I have owned this car since April 2021 and previously had a few similar situations when moving in the forward direction. Previously, the brake problem occurred while moving forward at very low speed pulling into parking places. The brake failed to activate, and I had to…”
Electrical system
“Electronic Parking Brake (EPB), 12V Battery/Electrical System. My vehicle's 12V battery failed, with the dealership measuring voltage below 10V during the event. This caused multiple simultaneous module malfunctions (confirmed by the dealer as caused by the battery failure), including a complete inability to move the vehicle after jump-starting on three separate attempts — the engine ran, but the vehicle would not drive despite a functioning alternator. The vehicle's steering wheel also locked, preventing the car from being pushed to a safe location. Approximately 3 months after this event, a routine service visit revealed the rear brake pads had worn from 8mm (measured at time of purchase) to 2mm (failed), while the front pads wore from 10mm to 7.8mm (normal wear) over the same period and mileage. The rear pads wore roughly 3 times faster than the front, which is inconsistent with normal vehicle operation, since front brakes handle proportionally more braking load and are fitted with larger rotors for this reason on this and virtually all vehicles. The rear brake caliper is the only caliper equipped with the EPB motor/actuator; the front calipers are purely…”
Engines, transmissions & drive
- EPA class
- Small Sport Utility Vehicle 2WD, Small Sport Utility Vehicle 4WD
- Engines
- 3.5L 6-cyl
- Transmissions
- Automatic (S8)
- Drive
- Front-Wheel Drive · All-Wheel Drive
- Fuel
- Regular Gasoline
Towing, payload and dimensions aren’t in the EPA or NHTSA data, so we don’t list them.
EPA fuel economy by version
| Version | City | Hwy | Comb. | Fuel / yr | CO₂ g/mi |
|---|---|---|---|---|---|
| RX 350 Auto (S8), 6 cyl, 3.5 L · Front-Wheel Drive | 20 | 27 | 23 | $2,700 | 391 |
| RX 350 AWD Auto (S8), 6 cyl, 3.5 L · All-Wheel Drive | 19 | 26 | 22 | $2,850 | 405 |
- 23mpg comb.
- 22mpg comb.
NHTSA 5-Star Safety Ratings
- Frontal crash
- 4 of 5
- Side crash
- 5 of 5
- Side pole
- 5 of 5
- Rollover
- 4 of 5
- Rollover risk
- 17.9%
- Frontal crash
- 4 of 5
- Side crash
- 5 of 5
- Side pole
- 5 of 5
- Rollover
- 4 of 5
- Rollover risk
- 16.4%
- Frontal crash
- 4 of 5
- Side crash
- 5 of 5
- Side pole
- 5 of 5
- Rollover
- 4 of 5
- Rollover risk
- 16.4%
- Frontal crash
- 4 of 5
- Side crash
- 5 of 5
- Side pole
- 5 of 5
- Rollover
- 4 of 5
- Rollover risk
- 17.9%
Maintenance basics
| Item | Miles | Time | Note |
|---|---|---|---|
| Engine oil & filter | 5,000–10,000 mi | 6–12 months | Follow the oil-life monitor if fitted |
| Tire rotation | 5,000–7,500 mi | Every oil change | Check pressure monthly |
| Engine air filter | 15,000–30,000 mi | 1–2 years | Sooner in dusty areas |
| Cabin air filter | 15,000–25,000 mi | 1–2 years | |
| Brake fluid | — | 2–3 years | Absorbs moisture over time |
| Coolant | 60,000–100,000 mi | 5–10 years | Long-life coolants last longer |
| Spark plugs | 60,000–100,000 mi | — | Iridium/platinum plugs at the long end |
| 12V battery | — | 3–5 years | Heat shortens battery life |
- Engine oil & filter5,000–10,000 mi
6–12 months - Tire rotation5,000–7,500 mi
Every oil change - Engine air filter15,000–30,000 mi
1–2 years - Cabin air filter15,000–25,000 mi
1–2 years - Brake fluid—
2–3 years - Coolant60,000–100,000 mi
5–10 years - Spark plugs60,000–100,000 mi
— - 12V battery—
3–5 years
2021 RX 350 questions
How many recalls does the 2021 Lexus RX 350 have?
0 recalls found in NHTSA data as of Nov 10, 2026.
What are the most common 2021 Lexus RX 350 problems?
Owners filed 71 complaints with NHTSA. The most-cited components are air bags (47), structure (5), electrical system (4). Complaints are unverified owner reports and aren't adjusted for how many cars were sold.
What MPG does the 2021 Lexus RX 350 get?
The EPA rates the 2021 Lexus RX 350 at 22–23 mpg combined, depending on engine and drivetrain (2 versions rated).
How safe is the 2021 Lexus RX 350?
NHTSA's New Car Assessment Program gives the 2021 Lexus RX 350 4–5 out of 5 stars overall.