2022 Lexus RX 350Recalls, problems, MPG & safety
NHTSA lists 0 safety recalls and 39 owner complaints for the 2022 Lexus RX 350. Most complaints involve electrical system (8) and fuel/propulsion system (5). The EPA rates it 22–23 mpg combined, and NHTSA gives it 4 stars overall.
Safety recalls
Owner complaints by component
- Electrical system8
- Fuel/propulsion system5
- Power train4
- Engine4
- Tires4
- Service brakes3
- Vehicle speed control2
- Exterior lighting2
- Air bags2
Complaints are unverified owner reports to NHTSA and are not normalized for sales volume. One complaint can cite several components.
What owners report most
Electrical system
“my rear windshield shattered - I was not driving - I was not using the rear defrost - I simply put car in reverse and when I looked back my glass was shattered. 08/09/2026”
Fuel/propulsion system
“My wife was driving the subject car She intended to come off the road to give a way to on coming car. She got in naghbour's drive way and intended move 10 feet. When she tried to put more gas to move the car was hyper accepting drove 50 feets away and hit naghbour's ion gate and stopped. When she back off it did again and hit street lamp. It did two more time. Ended up damaging 4 corners of the car and all the material that the car hit. I could not understand that she hit the 4 corner of the car. That is why I suspected engine problem. When I tried the same movement nàghbour came out and worry that the car will do the same thing. While I was talking to him. He told me he has security camera and he noticed excess unning of the engine. He sent me the clip I couldn't see the car but certainly I could hear the engine. The end of the report.”
Power train
“The vehicle has exhibited intermittent drivability and safety-related concerns after a prior collision repair. The concerns include delayed acceleration/engagement, abnormal jerking or stopping behavior, and elevated RPM behavior during real-world driving. The most recent documented event occurred on July 27, 2026, while the vehicle was in Drive at approximately 50 mph with cruise/driver-assist indicators illuminated. The tachometer appeared near the 4,000 RPM range. The event was captured by video/screenshot and the vehicle is available for inspection upon request. The issue creates a safety concern because delayed acceleration, unexpected jerking/stopping, or abnormal RPM behavior could affect the driver’s ability to safely merge, maintain speed, respond to traffic, or control the vehicle during highway or road driving. The problem has been intermittent and has not always produced an active warning lamp. A Lexus dealer inspected/scanned the vehicle on May 21, 2026 and discussed Eco Mode/Normal Drive Mode, but the symptoms continued afterward. The vehicle has a documented post-repair history involving transmission cooler replacement, transmission-fluid…”
Engines, transmissions & drive
- EPA class
- Small Sport Utility Vehicle 2WD, Small Sport Utility Vehicle 4WD
- Engines
- 3.5L 6-cyl
- Transmissions
- Automatic (S8)
- Drive
- Front-Wheel Drive · All-Wheel Drive
- Fuel
- Regular Gasoline
Towing, payload and dimensions aren’t in the EPA or NHTSA data, so we don’t list them.
EPA fuel economy by version
| Version | City | Hwy | Comb. | Fuel / yr | CO₂ g/mi |
|---|---|---|---|---|---|
| RX 350 Auto (S8), 6 cyl, 3.5 L · Front-Wheel Drive | 20 | 27 | 23 | $2,700 | 391 |
| RX 350 AWD Auto (S8), 6 cyl, 3.5 L · All-Wheel Drive | 19 | 26 | 22 | $2,850 | 405 |
- 23mpg comb.
- 22mpg comb.
NHTSA 5-Star Safety Ratings
- Frontal crash
- 4 of 5
- Side crash
- 5 of 5
- Side pole
- 5 of 5
- Rollover
- 4 of 5
- Rollover risk
- 16.4%
- Frontal crash
- 4 of 5
- Side crash
- 5 of 5
- Side pole
- 5 of 5
- Rollover
- 4 of 5
- Rollover risk
- 17.9%
Maintenance basics
| Item | Miles | Time | Note |
|---|---|---|---|
| Engine oil & filter | 5,000–10,000 mi | 6–12 months | Follow the oil-life monitor if fitted |
| Tire rotation | 5,000–7,500 mi | Every oil change | Check pressure monthly |
| Engine air filter | 15,000–30,000 mi | 1–2 years | Sooner in dusty areas |
| Cabin air filter | 15,000–25,000 mi | 1–2 years | |
| Brake fluid | — | 2–3 years | Absorbs moisture over time |
| Coolant | 60,000–100,000 mi | 5–10 years | Long-life coolants last longer |
| Spark plugs | 60,000–100,000 mi | — | Iridium/platinum plugs at the long end |
| 12V battery | — | 3–5 years | Heat shortens battery life |
- Engine oil & filter5,000–10,000 mi
6–12 months - Tire rotation5,000–7,500 mi
Every oil change - Engine air filter15,000–30,000 mi
1–2 years - Cabin air filter15,000–25,000 mi
1–2 years - Brake fluid—
2–3 years - Coolant60,000–100,000 mi
5–10 years - Spark plugs60,000–100,000 mi
— - 12V battery—
3–5 years
2022 RX 350 questions
How many recalls does the 2022 Lexus RX 350 have?
0 recalls found in NHTSA data as of Nov 10, 2026.
What are the most common 2022 Lexus RX 350 problems?
Owners filed 39 complaints with NHTSA. The most-cited components are electrical system (8), fuel/propulsion system (5), power train (4). Complaints are unverified owner reports and aren't adjusted for how many cars were sold.
What MPG does the 2022 Lexus RX 350 get?
The EPA rates the 2022 Lexus RX 350 at 22–23 mpg combined, depending on engine and drivetrain (2 versions rated).
How safe is the 2022 Lexus RX 350?
NHTSA's New Car Assessment Program gives the 2022 Lexus RX 350 4 out of 5 stars overall.