NHTSA lists 1 safety recall and 3 owner complaints for the 2018 Mercedes-Benz E 400 4Matic. Most complaints involve power train (2) and engine (1). The EPA rates it 21–23 mpg combined.
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2018 E 400 4MATIC Sedan, E 400 4MATIC Wagon, E 400 4MATIC Cabriolet, E 400 4MATIC Coupe, 2018-2020 Maybach S 560 4MATIC, S 560 4MATIC Coupe, S 450 4MATIC, 2019-2020 E 450 4MATIC Sedan, E 450 4MATIC Wagon, E 450 4MATIC Coupe, and E 450 4MATIC Cabriolet vehicles. The drive shaft universal joint may break, resulting in a sudden loss of drive power.
Complaints are unverified owner reports to NHTSA and are not normalized for sales volume. One complaint can cite several components.
Complaints for each E 400 4Matic model year we’ve synced.
Only one model year synced so far.
“The contact owns a 2018 Mercedes-Benz E400 4MATIC. The contact received notification of NHTSA Campaign Number: 26V216000 (POWER TRAIN); however, the part to do the recall repair was not yet available. The local dealer was contacted. The contact stated that the manufacturer had exceeded a reasonable amount of time for the recall repair. The manufacturer was made aware of the issue.”
“Component/System: The intake camshaft positioner/adjuster on cylinder bank 2 of the M276 V6 engine has failed, along with associated timing components. The vehicle (2018 Mercedes-Benz E400, VIN [XXX]) remains unrepaired and is available for inspection upon request. Safety Risk: The engine produces a loud metallic rattle on cold starts, indicating loss of proper camshaft timing control. If unaddressed, camshaft timing deviation can progress to timing chain failure, which on interference engines can cause valve-to-piston contact and sudden, severe engine damage or loss of power while driving, posing a risk to vehicle control. Confirmed by Dealer: Yes. Mercedes-Benz of Catonsville (RO# [XXX]) diagnosed the issue and confirmed stored fault code P002177, indicating the intake camshaft position on cylinder bank 2 deviates from its specified value. The dealer's own notes state camshaft adjusters "are prone to failure and commonly damage camshafts when they fail." Manufacturer Notified: I contacted Mercedes-Benz USA directly (Case #[XXX]) to request they address this repair, citing that this camshaft/timing failure is a known, recurring issue on M276-equipped vehicles,…”
Towing, payload and dimensions aren’t in the EPA or NHTSA data, so we don’t list them.
| Version | City | Hwy | Comb. | Fuel / yr | CO₂ g/mi |
|---|---|---|---|---|---|
| E400 4matic Auto 9-spd, 6 cyl, 3.0 L, Turbo · 4-Wheel Drive | 20 | 27 | 23 | $3,250 | 396 |
| E400 4matic Convertible Auto 9-spd, 6 cyl, 3.0 L, Turbo · 4-Wheel Drive | 20 | 25 | 22 | $3,400 | 404 |
| E400 4matic Coupe Auto 9-spd, 6 cyl, 3.0 L, Turbo · 4-Wheel Drive | 20 | 26 | 22 | $3,400 | 394 |
| E400 4matic (station wagon) Auto 9-spd, 6 cyl, 3.0 L, Turbo · 4-Wheel Drive | 19 | 25 | 21 | $3,600 | 417 |
| Item | Miles | Time | Note |
|---|---|---|---|
| Engine oil & filter | 5,000–10,000 mi | 6–12 months | Follow the oil-life monitor if fitted |
| Tire rotation | 5,000–7,500 mi | Every oil change | Check pressure monthly |
| Engine air filter | 15,000–30,000 mi | 1–2 years | Sooner in dusty areas |
| Cabin air filter | 15,000–25,000 mi | 1–2 years | |
| Brake fluid | — | 2–3 years | Absorbs moisture over time |
| Coolant | 60,000–100,000 mi | 5–10 years | Long-life coolants last longer |
| Spark plugs | 60,000–100,000 mi | — | Iridium/platinum plugs at the long end |
| 12V battery | — | 3–5 years | Heat shortens battery life |
1 safety recall as of Nov 13, 2026, according to NHTSA. Recall repairs are free at a dealer. Check your VIN to see whether your car is included and whether the repair was done.
Owners filed 3 complaints with NHTSA. The most-cited components are power train (2), engine (1). Complaints are unverified owner reports and aren't adjusted for how many cars were sold.
The EPA rates the 2018 Mercedes-Benz E 400 4Matic at 21–23 mpg combined, depending on engine and drivetrain (4 versions rated).