NHTSA lists 1 safety recall and 7 owner complaints for the 2025 Mercedes-Benz GLS 450 4Matic. Most complaints involve service brakes (2) and electrical system (2). The EPA rates it 21 mpg combined.
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2024 GLE 350 4MATIC, 2025 GLE 450e 4MATIC, GLE 450 4MATIC Coupe, GLE 450 4MATIC, GLS 450 4MATIC, Maybach GLS 600 4MATIC, AMG GLE 53 4MATIC, AMG GLE 53 4MATIC Coupe, AMG GLE 63 S 4MATIC Coupe, and AMG GLS 63 4MATIC vehicles. The multi-purpose camera and the rearview mirror may be insufficiently attached to the windshield and may detach.
Complaints are unverified owner reports to NHTSA and are not normalized for sales volume. One complaint can cite several components.
Complaints for each GLS 450 4Matic model year we’ve synced.
Only one model year synced so far.
“Brake pads completely worn after 11K miles - this seems like premature wear and like there is a potential issue with the braking system on the GLS450.”
“The contact owns a 2025 Mercedes-Benz GLS450 4Matic. The contact stated that while driving at various speeds, a safety feature with a white speed limit sign started flashing on the instrument cluster. The contact stated the flashing was a constant issue. The vehicle was taken to the local dealer several times. The contact was informed by the dealer that it was a known issue and that the manufacturer was still developing a fix. The vehicle was not repaired. The manufacturer was informed of the failure. The failure mileage was 5,265.”
“We recently noticed visible damage to one of the seatbelts in our 2025 Mercedes-Benz GLS450. The affected component is the seatbelt webbing. The belt has visible fraying and pulled/cut fibers along the edge in two separate spots near the area where the belt retracts. The vehicle is very new, and the damage appears abnormal for a safety-related component. The damage is localized near the belt path/retractor area, and we are concerned it may be related to an issue with the seatbelt path, retractor mechanism, surrounding trim, alignment, or another defect in the restraint system. The component is available for inspection upon request. This creates a safety concern because the seatbelt is a critical occupant restraint system. If the webbing fibers are damaged, the seatbelt may not perform as intended in a crash or sudden stop. We are currently avoiding use of that seating position until the issue is inspected and resolved. The problem has been brought to the attention of a Mercedes-Benz dealer. The dealer quoted approximately $2,250 to replace the affected seatbelt and indicated that it would not be covered under warranty. To our knowledge, the dealer has not yet…”
Towing, payload and dimensions aren’t in the EPA or NHTSA data, so we don’t list them.
| Version | City | Hwy | Comb. | Fuel / yr | CO₂ g/mi |
|---|---|---|---|---|---|
| GLS450 4matic Auto 9-spd, 6 cyl, 3.0 L, Turbo, Sup Charg · All-Wheel Drive | 19 | 24 | 21 | $3,600 | 428 |
| Item | Miles | Time | Note |
|---|---|---|---|
| Engine oil & filter | 5,000–10,000 mi | 6–12 months | Follow the oil-life monitor if fitted |
| Tire rotation | 5,000–7,500 mi | Every oil change | Check pressure monthly |
| Engine air filter | 15,000–30,000 mi | 1–2 years | Sooner in dusty areas |
| Cabin air filter | 15,000–25,000 mi | 1–2 years | |
| Brake fluid | — | 2–3 years | Absorbs moisture over time |
| Coolant | 60,000–100,000 mi | 5–10 years | Long-life coolants last longer |
| Spark plugs | 60,000–100,000 mi | — | Iridium/platinum plugs at the long end |
| 12V battery | — | 3–5 years | Heat shortens battery life |
1 safety recall as of Nov 12, 2026, according to NHTSA. Recall repairs are free at a dealer. Check your VIN to see whether your car is included and whether the repair was done.
Owners filed 7 complaints with NHTSA. The most-cited components are service brakes (2), electrical system (2), seat belts (1). Complaints are unverified owner reports and aren't adjusted for how many cars were sold.
The EPA rates the 2025 Mercedes-Benz GLS 450 4Matic at 21 mpg combined, depending on engine and drivetrain (1 version rated).