NHTSA lists 1 safety recall and 225 owner complaints for the 2007 Lexus RX350. Most complaints involve engine (44) and structure (31). The EPA rates it 19–20 mpg combined.
TOYOTA IS RECALLING CERTAIN MODEL YEAR 2004-2006 HIGHLANDER, HIGHLANDER HYBRID, AND MODEL YEAR 2004-2007 LEXUS RX330, RX350, AND RX400H VEHICLES. IF THE FORWARD RETENTION CLIP USED TO SECURE THE FLOOR CARPET COVER, WHICH IS LOCATED IN FRONT OF THE CENTER CONSOLE, IS NOT INSTALLED PROPERLY THE COVER MAY LEAN TOWARD THE ACCELERATOR PEDAL AND INTERFERE WITH THE ACCELERATOR PEDAL ARM.
Complaints are unverified owner reports to NHTSA and are not normalized for sales volume. One complaint can cite several components.
“I PURCHASED A USED 2007 LEXUS RX350 FOR MY 16 YEAR OLD DAUGHTER. IT HAD A LITTLE OVER 100K MILES. EVERYTHING WORKED PERFECTLY, NO COMPLAINTS WHATSOEVER. UNTIL, MY SON BORROWED IT, AND WHILE HE WAS DRIVING IT, HE SAID IT QUIT. HE LOST ALL POWER STEERING, SO HE PULLED OVER. WE CALLED A TOW TRUCK TO TOW IT TO A MECHANIC. WHEN THE MECHANIC CALLED ME, HE SAID THE OIL COOLING LINE BUSTED, WHICH MADE THE OIL PUMP EMPTY THE ENGINE'S OIL. HE SAID IT WOULD NEED A WHOLE NEW ENGINE. HE SAID THE CAR IS WORTH NOTHING. I PAID $9K FOR THIS CAR A YEAR AGO, AND NOW IT IS NOT WORTH $100. THE MECHANIC SAID THIS IS A KNOWN PROBLEM FOR TOYOTA/LEXUS, BUT THERE WAS NO RECALL. TO ME - THIS IS UNACCEPTABLE. IN MY OPINION, SINCE TOYOTA KNEW OF THIS PROBLEM, BUT DIDN'T RECALL IT, THEY EITHER NEED TO COVER THE COST OF A NEW ENGINE, OR BUY THE CAR BACK FROM ME. I AM VERY UPSET OVER THIS.”
“I saw on the internet while I was looking for new mats this year my Lexus RX 350, 2007, vin [XXX] was recalled for the dashboard until May 2017. During 2013 through 2018; my husband left me for my friend; both my sons were shot in different cities; one in Nashville, and one in Denver Colorado. The one in Nashville, was shot 10 times by his roommate who forgot he had a roommate. Fortunately, he turned around so his laptop in his backpack got the bullet which would have killed him. He was left with a dominant disabled arm. He had just come back from Las Vegas working with Jason Aldean as a cameraman and saw the bloody massacre from the shooters. My oldest lives in Denver. He was shot and killed by the police on a domestic call. They overreacted. My ex-husband would not let me come to the funeral or visit the son in Nashville when he was hurt. I was not able to focus on anything else during that time. When I saw the recall on the Internet this year, I called and requested a reprieve. I was turned down. I wrote a letter to Lexus. Again I was turned down. I am [XXX] and [XXX]. I’m still driving my Lexus 2007 and plan to the rest of my life. I didn’t see the mail…”
“Electrical system malfunction began (to my best calculation & recollection) in summer 2021 with the first of four battery malfunctions in one year. Each time, AAA discovered low battery response and recommended battery replacement. This time around, battery was replaced about two weeks prior, due to battery failure/AAA reporting would not accept charge. THE NEW BATTERY FAILED (8/3) and the starter broke while attempting to charge. Mechanic repaired starter and battery accepted the charge. No problem, right? Wrong. This driver drove about 30 miles and while driving, the electrical system shut down altogether. With I believe ALL WARNING LIGHTS LIGHTING UP, extremely dangerous situation. NO BREAKING, NO STEERING, NO WARNING. Fortunately, it occurred in a suburban residential area as opposed to the highway. SECOND tow to my mechanic and now, after a full week, no diagnosis, though the car has been running in the shop. This is an intermittent problem. I suspect the alternator.”
Towing, payload and dimensions aren’t in the EPA or NHTSA data, so we don’t list them.
| Version | City | Hwy | Comb. | Fuel / yr | CO₂ g/mi |
|---|---|---|---|---|---|
| RX 350 2WD Auto (S5), 6 cyl, 3.5 L · Front-Wheel Drive | 18 | 23 | 20 | $3,850 | 444 |
| RX 350 2WD Auto 5-spd, 6 cyl, 3.5 L · Front-Wheel Drive | 18 | 23 | 20 | $3,850 | 444 |
| RX 350 4WD Auto (S5), 6 cyl, 3.5 L · 4-Wheel or All-Wheel Drive | 17 | 22 | 19 | $4,050 | 468 |
| RX 350 4WD Auto 5-spd, 6 cyl, 3.5 L · 4-Wheel or All-Wheel Drive | 17 | 22 | 19 | $4,050 | 468 |
| Item | Miles | Time | Note |
|---|---|---|---|
| Engine oil & filter | 5,000–10,000 mi | 6–12 months | Follow the oil-life monitor if fitted |
| Tire rotation | 5,000–7,500 mi | Every oil change | Check pressure monthly |
| Engine air filter | 15,000–30,000 mi | 1–2 years | Sooner in dusty areas |
| Cabin air filter | 15,000–25,000 mi | 1–2 years | |
| Brake fluid | — | 2–3 years | Absorbs moisture over time |
| Coolant | 60,000–100,000 mi | 5–10 years | Long-life coolants last longer |
| Spark plugs | 60,000–100,000 mi | — | Iridium/platinum plugs at the long end |
| 12V battery | — | 3–5 years | Heat shortens battery life |
1 safety recall as of Nov 10, 2026, according to NHTSA. Recall repairs are free at a dealer. Check your VIN to see whether your car is included and whether the repair was done.
Owners filed 225 complaints with NHTSA. The most-cited components are engine (44), structure (31), steering (29). Complaints are unverified owner reports and aren't adjusted for how many cars were sold.
The EPA rates the 2007 Lexus RX350 at 19–20 mpg combined, depending on engine and drivetrain (4 versions rated).